Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28211325 | 0.84 | KCNT1 (0.43) | FKBP1AKMT2AGLAMAPK1MEN1 | |
| SCHEMBL16371627 | 0.78 | FKBP1A (0.44) | FKBP1AKMT2AGLACHRNB2CHRNB4 | |
| SCHEMBL7839074 | 0.77 | FKBP1A (0.66) | FKBP1AKMT2AGLAPOLBHPGD | |
| SCHEMBL28210752 | 0.76 | KEAP1 (0.52) | FKBP1AKMT2AGLAPOLBMEN1 | |
| SCHEMBL4001428 | 0.76 | POLB (0.56) | FKBP1AKMT2AGLAPOLBKDM4E | |
| SCHEMBL2512424 | 0.75 | FKBP1A (0.69) | FKBP1AKMT2AGLAHPGDMAPK1 | |
| SCHEMBL4710815 | 0.72 | HTR6 (0.51) | FKBP1AKMT2AGLAPOLB | |
| SCHEMBL30916886 | 0.72 | FKBP1A (0.47) | FKBP1AKMT2AGLAPOLBHPGD | |
| SCHEMBL1853129 | 0.72 | POLB (0.71) | FKBP1AKMT2AGLAPOLBMEN1 | |
| SCHEMBL28211411 | 0.72 | TRPV4 (0.50) | FKBP1AKMT2AGLAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107980040-A | 1,3,4- oxadiazoles sulfamide derivative as 6 inhibitor of histone deacetylase enzyme and the medical composition containing it | 株式会社钟根堂 | 2018-05-01 | — | — | CN | disclosed |