Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24327309 | 0.84 | LMNA (0.36) | TSHRCYP3A4LMNAHSD17B10ALDH1A1 | |
| SCHEMBL11491934 | 0.84 | TSHR (0.58) | TSHRCYP3A4LMNAHSD17B10ALDH1A1 | |
| SCHEMBL12062694 | 0.81 | LMNA (0.41) | TSHRCYP3A4LMNAHSD17B10ALDH1A1 | |
| SCHEMBL24313567 | 0.79 | L3MBTL1 (0.40) | TSHRCYP3A4LMNAHSD17B10ALDH1A1 | |
| SCHEMBL23907096 | 0.76 | NQO1 (0.33) | TSHRCYP3A4LMNANQO1BPTF | |
| SCHEMBL18023036 | 0.76 | TLR8 (0.50) | ALDH1A1MAPTMEN1MAPK1KMT2A | |
| SCHEMBL31461219 | 0.76 | HPGD (0.51) | TSHRLMNAALDH1A1HPGDPOLB | |
| SCHEMBL3859532 | 0.76 | HPGD (0.47) | TSHRLMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL24196687 | 0.75 | ALDH1A1 (0.39) | TSHRCYP3A4HSD17B10ALDH1A1KDM4E | |
| SCHEMBL28859629 | 0.74 | TLR8 (0.34) | TSHRCYP3A4LMNAHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083803-B | A kind of synthetic method of marine natural products Puupehedione | 威海惠安康生物科技有限公司 | 2018-05-04 | — | — | CN | claimed |