Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.65 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 4/20 | 0.51 |
| ▸ | MMP3 | P08254 | 4/20 | 0.50 |
| ▸ | RORC | P51449 | 2/20 | 0.50 |
| ▸ | AGER | Q15109 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954421 | 0.88 | TAS2R14 (0.53) | TAS2R14GLACNR2MMP3RORC | |
| SCHEMBL5190476 | 0.87 | TAS2R14 (0.63) | TAS2R14GLACNR2MMP3RORC | |
| SCHEMBL8629669 | 0.86 | TAS2R14 (0.55) | TAS2R14GLACNR2MMP3RORC | |
| SCHEMBL9187490 | 0.85 | GLA (0.53) | TAS2R14GLACNR2AGERMAPT | |
| SCHEMBL16542984 | 0.83 | AGER (0.53) | TAS2R14GLAAGERMAPTMCOLN3 | |
| SCHEMBL7347286 | 0.83 | MMP3 (0.76) | TAS2R14MMP3MMP1MMP2MMP9 | |
| SCHEMBL7081150 | 0.82 | MEN1 (0.60) | TAS2R14GLACNR2MMP3RORC | |
| SCHEMBL27550249 | 0.81 | AGER (0.47) | TAS2R14GLACNR2AGERMAPT | |
| SCHEMBL10692733 | 0.80 | GLA (0.59) | TAS2R14GLACNR2AGERMAPT | |
| SCHEMBL9485009 | 0.80 | GLA (0.51) | TAS2R14GLACNR2AGERMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107954906-B | Synthetic method of aryl sulfonyl tertiary amine compound | 西北师范大学 | 2020-10-16 | — | — | CN | disclosed |
| CN-107954906-A | A kind of synthetic method of arylsulfonyl tertiary amine compounds | 西北师范大学 | 2018-04-24 | — | — | CN | disclosed |