Oxyquinoline

Oxyquinoline

SCHEMBL28215871

C=C(C)C(=O)O.Oc1cccc2cccnc12

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 2/20 0.68
METAP1 P53582 2/20 0.68
MMP2 P08253 1/20 0.68
CHRM1 P11229 1/20 0.68
TSHR P16473 1/20 0.68
COMT P21964 1/20 0.68
ADRA1A P35348 1/20 0.68
HDAC8 Q9BY41 1/20 0.68
ALDH1A1 P00352 5/20 0.63
ALOX12 P18054 2/20 0.63
LMNA P02545 2/20 0.63
KDM4E B2RXH2 5/20 0.63
KMT2A Q03164 3/20 0.46
PARP1 P09874 1/20 0.46
TDP1 Q9NUW8 2/20 0.44
POLB P06746 1/20 0.44
HPGD P15428 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KDM4A O75164 2/20 0.44
EGLN1 Q9GZT9 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyquinoline SCHEMBL2867503 0.90 MMP2 (0.78) METAP2METAP1MMP2CHRM1TSHR
Oxyquinoline SCHEMBL4465896 0.90 MMP2 (0.78) METAP2METAP1MMP2CHRM1TSHR
Oxyquinoline SCHEMBL15568316 0.88 MMP2 (0.75) METAP2METAP1MMP2CHRM1TSHR
Oxyquinoline SCHEMBL5965842 0.88 MMP2 (0.81) METAP2METAP1MMP2CHRM1TSHR
Phenanthroline SCHEMBL28776402 0.86 LMNA (0.59) METAP2METAP1MMP2CHRM1TSHR
Oxyquinoline SCHEMBL27553390 0.86 MMP2 (0.78) METAP2METAP1MMP2CHRM1TSHR
Oxyquinoline SCHEMBL28459062 0.86 MMP2 (0.84) METAP2METAP1MMP2CHRM1TSHR
Oxyquinoline SCHEMBL28248001 0.85 TSHR (0.60) METAP2METAP1MMP2CHRM1TSHR
Oxyquinoline SCHEMBL866498 0.85 MMP2 (0.75) METAP2METAP1MMP2CHRM1TSHR
Oxyquinoline SCHEMBL27477171 0.84 MMP2 (0.81) METAP2METAP1MMP2CHRM1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107903647-A A kind of mildew resistant moistureproof and environmentally protective wood-plastic clad plate and preparation method thereof 安徽伊法拉电气有限公司 2018-04-13 CN disclosed