Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 2/20 | 0.75 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.75 |
| ▸ | COMT | P21964 | 1/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.75 |
| ▸ | METAP2 | P50579 | 1/20 | 0.75 |
| ▸ | METAP1 | P53582 | 1/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxyquinoline SCHEMBL27477171 | 0.93 | MMP2 (0.81) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL8605182 | 0.93 | MMP2 (0.81) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL5965842 | 0.93 | MMP2 (0.81) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL2867503 | 0.91 | MMP2 (0.78) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL4465896 | 0.91 | MMP2 (0.78) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL27553390 | 0.91 | MMP2 (0.78) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL15568316 | 0.89 | MMP2 (0.75) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL15568317 | 0.88 | MMP2 (0.72) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL28459062 | 0.87 | MMP2 (0.84) | MMP2TSHRCHRM1COMTADRA1A | |
| Oxyquinoline SCHEMBL28915558 | 0.87 | TSHR (0.91) | MMP2TSHRCHRM1COMTADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058074-B2 | 8-hydroxyquinoline acetamide compound, 8-hydroxy quinoline thioamide compound and use thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-11-15 | — | — | US | claimed |
| US-20080044913-A1 | NOVEL 8-HYDROXYQUINOLINE ACETAMIDE COMPOUND, 8-HYDROXY QUINOLINE THIOAMIDE COMPOUND AND USE THEREOF | CHUNG-ANG UNIVERSITY INUDSTRY-ACADEMY COOPERATION FOUNDATION (KR) | 2008-02-21 | — | — | US | claimed |
| US-20180017541-A1 | SYSTEMS AND METHODS TO DETECT AND MEASURE MATERIALS IN OIL | KINARD WILLIAM BRIAN (US) | 2018-01-18 | — | — | US | disclosed |
| WO-2018013473-A1 | SYSTEMS AND METHODS TO DETECT AND MEASURE MATERIALS IN OIL | KINARD WILLIAM BRIAN (US) | 2018-01-18 | — | — | WO | disclosed |
| US-8377698-B2 | 8-hydroxyquinoline acetamide compound, 8-hydroxy quinoline thioamide compound and use thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2013-02-19 | — | — | US | disclosed |
| US-8377698-B2 | 8-hydroxyquinoline acetamide compound, 8-hydroxy quinoline thioamide compound and use thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2013-02-19 | — | — | US | disclosed |
| US-8377698-B2 | 8-hydroxyquinoline acetamide compound, 8-hydroxy quinoline thioamide compound and use thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2013-02-19 | — | — | US | disclosed |
| US-20120077275-A1 | NOVEL 8-HYDROXYQUINOLINE ACETAMIDE COMPOUND, 8-HYDROXY QUINOLINE THIOAMIDE COMPOUND AND USE THEREOF | SAMSUNG ELECTRONICS CO.. LTD. (KR) | 2012-03-29 | — | — | US | disclosed |
| US-20120077275-A1 | NOVEL 8-HYDROXYQUINOLINE ACETAMIDE COMPOUND, 8-HYDROXY QUINOLINE THIOAMIDE COMPOUND AND USE THEREOF | SAMSUNG ELECTRONICS CO.. LTD. (KR) | 2012-03-29 | — | — | US | disclosed |
| US-8058074-B2 | 8-hydroxyquinoline acetamide compound, 8-hydroxy quinoline thioamide compound and use thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-11-15 | — | — | US | disclosed |
| US-8058074-B2 | 8-hydroxyquinoline acetamide compound, 8-hydroxy quinoline thioamide compound and use thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-11-15 | — | — | US | disclosed |
| US-8058074-B2 | 8-hydroxyquinoline acetamide compound, 8-hydroxy quinoline thioamide compound and use thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-11-15 | — | — | US | disclosed |
| US-20080044913-A1 | NOVEL 8-HYDROXYQUINOLINE ACETAMIDE COMPOUND, 8-HYDROXY QUINOLINE THIOAMIDE COMPOUND AND USE THEREOF | CHUNG-ANG UNIVERSITY INUDSTRY-ACADEMY COOPERATION FOUNDATION (KR) | 2008-02-21 | — | — | US | disclosed |
| US-20080044913-A1 | NOVEL 8-HYDROXYQUINOLINE ACETAMIDE COMPOUND, 8-HYDROXY QUINOLINE THIOAMIDE COMPOUND AND USE THEREOF | CHUNG-ANG UNIVERSITY INUDSTRY-ACADEMY COOPERATION FOUNDATION (KR) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080044913-A1 | NOVEL 8-HYDROXYQUINOLINE ACETAMIDE COMPOUND, 8-HYDROXY QUINOLINE THIOAMIDE COMPOUND AND USE THEREOF | TST, TMT1A, HDHD5 | MMP2 4479/4885TSHR 1983/4885CHRM1 2349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.