SCHEMBL28217032

SCHEMBL28217032

Cn1c2ccccc2c2cc(C=Cc3ccccc3)ccc21

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.55
KDM4E B2RXH2 5/20 0.53
MAPT P10636 4/20 0.51
ALDH1A1 P00352 4/20 0.51
KMT2A Q03164 4/20 0.51
HPGD P15428 3/20 0.51
MEN1 O00255 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
HTT P42858 1/20 0.51
HSD17B10 Q99714 1/20 0.51
PSEN1 P49768 1/20 0.49
PSEN2 P49810 1/20 0.49
APH1B Q8WW43 1/20 0.49
NCSTN Q92542 1/20 0.49
APH1A Q96BI3 1/20 0.49
PSENEN Q9NZ42 1/20 0.49
LMNA P02545 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
POLB P06746 2/20 0.46
RAB9A P51151 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17722994 0.95 IP6K1 (0.49) GPR3KDM4EMAPTALDH1A1KMT2A
SCHEMBL14366792 0.95 GPR3 (0.61) GPR3KDM4EMAPTALDH1A1KMT2A
SCHEMBL12419783 0.91 GPR3 (0.57) GPR3KDM4EMAPTALDH1A1KMT2A
SCHEMBL12419784 0.84 GPR3 (0.57) GPR3KDM4EMAPTALDH1A1KMT2A
SCHEMBL23918466 0.84 KIF11 (0.51) GPR3KDM4EMAPTALDH1A1KMT2A
SCHEMBL10123618 0.84 KDM4E (0.44) GPR3KDM4EMAPTALDH1A1KMT2A
SCHEMBL18473305 0.82 KDM4E (0.58) KDM4EMAPTALDH1A1KMT2AHPGD
SCHEMBL12306232 0.82 KDM4E (0.58) KDM4EMAPTALDH1A1KMT2AHPGD
SCHEMBL18231256 0.82 GPR3 (0.50) GPR3KDM4EMAPTALDH1A1KMT2A
SCHEMBL133176 0.82 KDM4E (0.65) KDM4EMAPTALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108003088-A A kind of synthetic method of 1- (9- carbazyls) -2- phenyl -1,2- second derovatives 辽宁科技大学 2018-05-08 CN disclosed