Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023619 | 0.93 | KDM4E (0.52) | TDP2CHEK1KDM4ENPC1ALDH1A1 | |
| Fluorene SCHEMBL445897 | 0.90 | MMP3 (0.54) | TDP2CHEK1KDM4ENPC1ALDH1A1 | |
| SCHEMBL23581451 | 0.88 | ALDH1A1 (0.57) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| SCHEMBL27614921 | 0.86 | NPC1 (0.52) | TDP2KDM4ENPC1ALDH1A1LMNA | |
| Fluorene SCHEMBL29255665 | 0.86 | MMP3 (0.62) | CHEK1KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL2763754 | 0.84 | ALDH1A1 (0.53) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| SCHEMBL28440412 | 0.84 | ALDH1A1 (0.59) | TDP2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL29682646 | 0.84 | ALDH1A1 (0.53) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| SCHEMBL30680392 | 0.84 | ALDH1A1 (0.53) | KDM4ENPC1ALDH1A1LMNAMAPT | |
| Fluorene SCHEMBL9397891 | 0.84 | MAOA (0.54) | CHEK1KDM4ENPC1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110295037-A | Thick 2H- naphtho- [2,1-b] pyrans photochromic compound of indenes and preparation method thereof | 南开大学 | 2019-10-01 | — | — | CN | claimed |
| CN-110295037-A | Thick 2H- naphtho- [2,1-b] pyrans photochromic compound of indenes and preparation method thereof | 南开大学 | 2019-10-01 | — | — | CN | disclosed |
| CN-110295037-A | Thick 2H- naphtho- [2,1-b] pyrans photochromic compound of indenes and preparation method thereof | 南开大学 | 2019-10-01 | — | — | CN | disclosed |
| CN-104903432-B | The viscosity improver of unsaturated acylating reagent and polycyclic aromatic hydrocarbon grafting | 雪佛龙奥伦耐有限责任公司 | 2018-04-24 | — | — | CN | disclosed |
| CN-104903432-A | Viscosity improver grafted with unsaturated acylating agent and polyaromatic hydrocarbon | CHEVRON ORONITE CO | 2015-09-09 | — | — | CN | disclosed |