Fluorene

Fluorene

SCHEMBL29255665

Oc1ccc(-c2ccccc2)cc1.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 1/20 0.62
BCL2L1 Q07817 1/20 0.62
CHEK1 O14757 1/20 0.51
ESR1 P03372 5/20 0.49
ESR2 Q92731 4/20 0.49
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
SRD5A2 P31213 1/20 0.46
ABL1 P00519 1/20 0.45
ABCB1 P08183 1/20 0.45
BCR P11274 1/20 0.45
MAOA P21397 1/20 0.45
MIF P14174 1/20 0.45
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
RAB9A P51151 2/20 0.44
HSD17B1 P14061 1/20 0.43
HSD17B2 P37059 1/20 0.43
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL445897 0.96 MMP3 (0.54) MMP3BCL2L1CHEK1ESR1ESR2
Fluorene SCHEMBL9397891 0.89 MAOA (0.54) CHEK1MEN1KMT2ASRD5A2ABL1
Fluorene SCHEMBL28949262 0.88 BCL2L1 (0.46) MMP3BCL2L1CHEK1ESR1ESR2
Fluorene SCHEMBL28777378 0.87 CA12 (0.55) CHEK1MEN1KMT2ASRD5A2MAOA
Fluorene SCHEMBL441983 0.87 CA12 (0.55) CHEK1MEN1KMT2ASRD5A2MAOA
Fluorene SCHEMBL233215 0.87 CA12 (0.55) CHEK1MEN1KMT2ASRD5A2MAOA
Fluorene SCHEMBL29204380 0.87 CA12 (0.55) CHEK1MEN1KMT2ASRD5A2MAOA
Fluorene SCHEMBL473154 0.87 MAOA (0.56) SRD5A2MAOALMNAMAPTRAB9A
SCHEMBL28217038 0.86 TDP2 (0.54) MMP3BCL2L1CHEK1ESR1ESR2
SCHEMBL28023619 0.86 KDM4E (0.52) CHEK1ESR1ESR2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117865916-A Multifunctional acid anhydride type reinforcing agent and preparation method and application thereof 长沙学院 2024-04-12 CN disclosed