Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 3/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503679 | 0.84 | TSHR (0.42) | PTK2BHSD17B10NPC1POLBTSHR | |
| SCHEMBL18261809 | 0.79 | PTK2B (0.41) | PTK2BALPGLMNANPC1POLB | |
| SCHEMBL28250517 | 0.77 | PTGS2 (0.43) | PTK2BALPGLMNAHSD17B10ALDH1A1 | |
| SCHEMBL18261827 | 0.77 | TSHR (0.55) | PTK2BALPGLMNANPC1POLB | |
| SCHEMBL4071095 | 0.75 | TSHR (0.57) | LMNAHSD17B10POLBTSHRALDH1A1 | |
| SCHEMBL4062734 | 0.75 | LMNA (0.41) | LMNAHSD17B10POLBTSHRALDH1A1 | |
| SCHEMBL30483161 | 0.75 | TSHR (0.57) | LMNAHSD17B10POLBTSHRALDH1A1 | |
| SCHEMBL10580121 | 0.75 | LMNA (0.41) | LMNAHSD17B10POLBTSHRALDH1A1 | |
| SCHEMBL1928791 | 0.75 | ACP3 (0.43) | LMNAHSD17B10TSHRALDH1A1ACP3 | |
| SCHEMBL19946640 | 0.75 | CRHBP (0.44) | LMNAHSD17B10TSHRCYP1A2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108040479-A | Hydrogen sulphide precursor and its conjugate | 乔治亚州立大学研究基金会股份有限公司 | 2018-05-15 | — | — | CN | disclosed |