Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787825 | 0.86 | MAOA (0.46) | MAOAPOLBHTR2BALDH1A1LMNA | |
| SCHEMBL29522447 | 0.79 | MAOA (0.61) | MAOAALDH1A1MAPTKDM4EBCHE | |
| SCHEMBL6902816 | 0.79 | MAOA (0.61) | MAOAALDH1A1MAPTKDM4EBCHE | |
| SCHEMBL4668953 | 0.79 | MAOA (0.56) | MAOAALDH1A1LMNAMAPTKDM4E | |
| SCHEMBL7103871 | 0.71 | TSHR (0.57) | MAOAHTR2BALDH1A1MAPTBCHE | |
| SCHEMBL5543262 | 0.69 | MAOA (0.46) | MAOAPOLBHTR2BALDH1A1LMNA | |
| SCHEMBL3284763 | 0.69 | PNMT (0.53) | MAOAHTR2BALDH1A1LMNAMAPT | |
| SCHEMBL30403300 | 0.69 | MAOA (0.56) | MAOAPOLBHTR2BALDH1A1LMNA | |
| SCHEMBL18457362 | 0.69 | MAOA (0.38) | MAOAALDH1A1LMNAMAPTKDM4E | |
| Fluorene SCHEMBL10905010 | 0.69 | MAOA (0.62) | MAOAHTR2BALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108129440-A | A kind of method of synthesis of chiral chromene derivative | 中国科学院大连化学物理研究所 | 2018-06-08 | — | — | CN | disclosed |