SCHEMBL28219230

SCHEMBL28219230

O=CNc1ccc2c(c1)C=CCN2

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
TNKS2 Q9H2K2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3503657 0.76 CYP2A6 (0.38) ALDH1A1TNKS2
SCHEMBL2194416 0.72 KDM4E (0.32)
SCHEMBL28849571 0.71 ALDH1A1 (0.36) ALDH1A1
SCHEMBL28062192 0.70 ALDH1A1 (0.35) ALDH1A1
SCHEMBL5957277 0.69 CYP2A6 (0.30)
SCHEMBL5333036 0.68 TGM2 (0.32)
SCHEMBL30695309 0.68 HTR5A (0.33)
SCHEMBL1257327 0.68 AHR (0.35) ALDH1A1
SCHEMBL8469855 0.68 ALDH1A1 (0.34) ALDH1A1
SCHEMBL9453911 0.68 DRD2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110430878-A Antitumor agent and bromine structural domain inhibitor FUJIFILM CORP 2019-11-08 CN disclosed
CN-108137505-A Nitrogen-containing heterocycle compound 富士胶片株式会社 2018-06-08 CN disclosed