Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13615662 | 0.78 | NFE2L2 (0.56) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30138202 | 0.78 | NFE2L2 (0.56) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| Ethyne SCHEMBL28542315 | 0.74 | NFE2L2 (0.52) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31147160 | 0.71 | NFE2L2 (0.54) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22721268 | 0.71 | NFE2L2 (0.54) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1475036 | 0.71 | NFE2L2 (0.54) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4518769 | 0.71 | NFE2L2 (0.54) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| Boric Acid SCHEMBL9334258 | 0.71 | CES2 (0.46) | NFE2L2ERN1 | |
| SCHEMBL28504927 | 0.69 | CYP1A2 (0.51) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2020074 | 0.68 | NFE2L2 (0.62) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1932896-B1 | Stilbene derivatives, liquid-crystal mixtures and electro-optical displays | MERCK PATENT GMBH (DE) | 2010-10-27 | — | — | EP | claimed |
| US-7732022-B2 | Stilbene derivatives, liquid-crystal mixtures and electro-optical displays | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-06-08 | — | — | US | claimed |
| US-20080149891-A1 | STILBENE DERIVATIVES, LIQUID-CRYSTAL MIXTURES AND ELECTRO-OPTICAL DISPLAYS | MERCK PATENT GESELLSCHAFT (DE) | 2008-06-26 | — | — | US | claimed |
| EP-1932896-A1 | Stilbene derivatives, liquid-crystal mixtures and electro-optical displays | MERCK PATENT GmbH (DE) | 2008-06-18 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080149891-A1 | STILBENE DERIVATIVES, LIQUID-CRYSTAL MIXTURES AND ELECTRO-OPTICAL DISPLAYS | SBDS, LSS, VCL | NFE2L2 2510/4885GRIN2D 67/4885GRIN3B 2102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.