Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2823409 | 0.86 | PPARD (0.42) | PPARD | |
| SCHEMBL2822346 | 0.86 | PPARD (0.41) | PPARDGRM5CYP2C9HPGDCYP2C19 | |
| SCHEMBL2822197 | 0.76 | GRM5 (0.43) | PPARDGRM5MEN1ALDH1A1PLA2G1B | |
| SCHEMBL2823406 | 0.74 | PPARD (0.43) | PPARD | |
| SCHEMBL2822191 | 0.67 | GRM5 (0.43) | PPARDGRM5ALDH1A1HPGDHTT | |
| SCHEMBL2827433 | 0.62 | PPARG (0.38) | PPARDGRM5HSD17B10 | |
| SCHEMBL30609566 | 0.60 | ALOX5 (0.54) | GRM5MEN1ALDH1A1PLA2G1BHSP90AA1 | |
| SCHEMBL18130082 | 0.60 | ALOX5 (0.54) | GRM5MEN1ALDH1A1PLA2G1BHSP90AA1 | |
| SCHEMBL11196418 | 0.60 | ALDH1A1 (0.61) | MEN1ALDH1A1PLA2G1BHSP90AA1CYP3A4 | |
| SCHEMBL10802712 | 0.59 | BCL2L1 (0.50) | ALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745003-B1 | NOVEL COMPOUNDS, THEIR PREPARATION AND USE | HIGH POINT PHARMACEUTICALS LLC (US) | 2010-10-27 | — | — | EP | claimed |