SCHEMBL282269

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10036436	0.91	ALDH1A1 (0.52)	ALDH1A1SMN1; SMN2LMNAMAPTMAPK1
	SCHEMBL30306155	0.91	ALDH1A1 (0.52)	ALDH1A1SMN1; SMN2LMNAMAPTMAPK1
	SCHEMBL4865184	0.88	HTR6 (0.62)	HTR6ALDH1A1SMN1; SMN2LMNAMAPT
	SCHEMBL16305338	0.86	ALDH1A1 (0.55)	ALDH1A1SMN1; SMN2LMNAMAPTMAPK1
	SCHEMBL10127825	0.84	KMT2A (0.47)	ALDH1A1SMN1; SMN2LMNAWDR5SIRT6
	SCHEMBL26426465	0.82	SIRT6 (0.51)	ALDH1A1SMN1; SMN2LMNAMAPTMAPK1
	SCHEMBL328462	0.82	WDR5 (0.49)	ALDH1A1SMN1; SMN2LMNAWDR5SIRT6
	SCHEMBL30464731	0.82	WDR5 (0.49)	ALDH1A1SMN1; SMN2LMNAWDR5SIRT6
	SCHEMBL30464729	0.82	ALDH1A1 (0.59)	ALDH1A1SMN1; SMN2LMNAMAPTMAPK1
	SCHEMBL10036442	0.82	ALDH1A1 (0.59)	ALDH1A1SMN1; SMN2LMNAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.