SCHEMBL28228501

SCHEMBL28228501

Clc1ccc(N2COC=N2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR3E A5X5Y0 1/20 0.34
HTR3B O95264 1/20 0.34
ADRB1 P08588 1/20 0.34
HTR3A P46098 1/20 0.34
HTR3D Q70Z44 1/20 0.34
HTR3C Q8WXA8 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
NOTUM Q6P988 5/20 0.33
MAPT P10636 5/20 0.33
F2 P00734 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LMNA P02545 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MGLL Q99685 1/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28861397 0.80 L3MBTL1 (0.35) ADRB1NOTUMMAPTF2SMN1; SMN2
SCHEMBL11132453 0.74 MAPT (0.41) NOTUMMAPTMEN1KMT2AALDH1A1
SCHEMBL981604 0.65 TP53 (0.42) HTR3EHTR3BADRB1HTR3AHTR3D
Hydrochloric Acid SCHEMBL28999664 0.64 TP53 (0.41) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL28707761 0.63 MGLL (0.39) MAPTSMN1; SMN2LMNAMEN1KMT2A
SCHEMBL17935877 0.63 MAPT (0.42) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL11071665 0.63 HTR3E (0.41) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL8308328 0.60 HTR3E (0.42) HTR3EHTR3BADRB1HTR3AHTR3D
SCHEMBL31263067 0.59 ALDH1A1 (0.36) SIGMAR1NOTUMMAPTSMN1; SMN2LMNA
SCHEMBL908024 0.59 ABL1 (0.67) HTR3EHTR3BADRB1HTR3AHTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106245053-B By the method for -2 (3H) -one derivative of carbon dioxide, aryl hydrazine and paraformaldehyde electro synthesis 1,3,4- oxadiazoles 华南理工大学 2018-06-22 CN disclosed