Pyrogallol

Pyrogallol

SCHEMBL4947548

C=C(C)C(=O)O.C=C(C)C(=O)O.Oc1cccc(O)c1O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
CA1 P00915 4/20 0.55
CA2 P00918 4/20 0.55
HPGD P15428 4/20 0.55
HSD17B10 Q99714 3/20 0.55
LMNA P02545 2/20 0.55
ALOX15 P16050 2/20 0.55
CA6 P23280 2/20 0.55
ADAMTS4 O75173 1/20 0.55
EGFR P00533 1/20 0.55
FYN P06241 1/20 0.55
MMP2 P08253 1/20 0.55
MMP9 P14780 1/20 0.55
MMP8 P22894 1/20 0.55
CDK2 P24941 1/20 0.55
MMP12 P39900 1/20 0.55
RECQL P46063 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ADAMTS5 Q9UNA0 1/20 0.55
THRB P10828 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrogallol SCHEMBL10407842 1.00 ALDH1A1 (0.55) ALDH1A1CA1CA2HPGDHSD17B10
Catechol SCHEMBL8185691 0.86 KDM4E (0.50) ALDH1A1CA1CA2HPGDHSD17B10
Catechol SCHEMBL6142654 0.86 KDM4E (0.50) ALDH1A1CA1CA2HPGDHSD17B10
Pyrogallol SCHEMBL8433563 0.85 CA1 (0.67) ALDH1A1CA1CA2HPGDHSD17B10
Pyrogallol SCHEMBL9797828 0.85 CA1 (0.67) ALDH1A1CA1CA2HPGDHSD17B10
Methacrylic Acid SCHEMBL28409298 0.83 HNF4A (0.51) ALDH1A1CA1CA2HPGDHSD17B10
Methacrylic Acid SCHEMBL10961547 0.83 CA2 (0.39) ALDH1A1CA1CA2HPGDHSD17B10
Pyrogallol SCHEMBL2266603 0.83 ALDH1A1 (0.71) ALDH1A1CA1CA2HPGDHSD17B10
Pyrogallol SCHEMBL225781 0.83 CA1 (0.71) ALDH1A1CA1CA2HPGDHSD17B10
Pyrogallol SCHEMBL2267521 0.80 ALDH1A1 (0.67) ALDH1A1CA1CA2HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080090742-A1 Compound and method of making the compound AFTON CHEMICAL CORPORATION 2008-04-17 US claimed
US-20080090742-A1 Compound and method of making the compound AFTON CHEMICAL CORPORATION 2008-04-17 US disclosed
EP-0334090-A2 Acrylate cured polyphosphazenes ETHYL CORPORATION (US) 1989-09-27 EP disclosed