Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | BAD | Q92934 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | NQO1 | P15559 | 3/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27288088 | 0.80 | KIF11 (0.47) | KIF11CDK4CCND1BCL2L1BAD | |
| SCHEMBL27632129 | 0.75 | KIF11 (0.46) | KIF11CDK4CCND1BCL2L1BAD | |
| SCHEMBL27466975 | 0.75 | KIF11 (0.46) | KIF11CDK4CCND1BCL2L1BAD | |
| SCHEMBL27430162 | 0.75 | KIF11 (0.46) | KIF11CDK4CCND1BCL2L1BAD | |
| SCHEMBL30662035 | 0.75 | BCL2L1 (0.48) | KIF11CDK4CCND1BCL2L1BAD | |
| SCHEMBL27772008 | 0.75 | HPRT1 (0.47) | KIF11CDK4CCND1BCL2L1BAD | |
| SCHEMBL27528878 | 0.75 | BCL2L1 (0.48) | KIF11CDK4CCND1BCL2L1BAD | |
| SCHEMBL27584193 | 0.74 | GNG2 (0.47) | KIF11CDK4CCND1BCL2L1BAD | |
| SCHEMBL28118478 | 0.73 | KIF11 (0.45) | KIF11NPC1CDK4CCND1BCL2L1 | |
| Ethane SCHEMBL27403615 | 0.71 | HPRT1 (0.50) | KIF11TSHRHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108440614-A | The inhibitor of sodium glucose cotransporter 1 | 莱西肯医药有限公司 | 2018-08-24 | — | — | CN | disclosed |