Ethylene Glycol

Ethylene Glycol

SCHEMBL28236334

C=Cc1ccc(B(O)OCC(C)(C)C)cc1.OCCO

nearest known ligand 0.33

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Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL28300855 0.81 CA2 (0.41)
SCHEMBL5074647 0.79 ALDH1A1 (0.39) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL31416487 0.75 ENPP2 (0.41) ALDH1A1
SCHEMBL11617621 0.74 ALDH1A1 (0.38) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL31416563 0.74 ORAI1 (0.43) ALDH1A1
SCHEMBL29055955 0.72 CHRNB2 (0.43) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
Ethylene Glycol SCHEMBL28428115 0.72 CA1 (0.46)
SCHEMBL31416532 0.71 HTT (0.35)
SCHEMBL11686471 0.71 ALDH1A1 (0.46) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7
SCHEMBL3314556 0.70 ALDH1A1 (0.50) ALDH1A1CHRNB2CHRNB4CHRNA3CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108341968-A A kind of dynamic aggregation object and its application 翁秋梅 2018-07-31 CN disclosed