Ethylene Glycol

Ethylene Glycol

SCHEMBL28300855

Cc1ccc(B(O)OCC(C)(C)C)cc1.OCCO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.41
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
ORAI1 Q96D31 1/20 0.41
ORAI2 Q96SN7 1/20 0.41
ORAI3 Q9BRQ5 1/20 0.41
TRPV6 Q9H1D0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL28236334 0.81 ALDH1A1 (0.33)
SCHEMBL31416487 0.80 ENPP2 (0.41) CA2
SCHEMBL31416563 0.79 ORAI1 (0.43) ORAI1ORAI2ORAI3TRPV6
SCHEMBL20338457 0.77 CA1 (0.52) CA2
Ethylene Glycol SCHEMBL28428115 0.76 CA1 (0.46) CA2
SCHEMBL6940800 0.76 LPL (0.33) CA2LPLLIPG
SCHEMBL31416532 0.76 HTT (0.35)
SCHEMBL20338444 0.75 NUDT1 (0.35)
SCHEMBL5953336 0.74 LPL (0.50) CA2LPLLIPGORAI1ORAI2
SCHEMBL24220348 0.73 KMT2A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824520-B Preparation method of cis-4-methylcyclohexylamine 苏州海犇药业有限公司 2021-07-23 CN claimed
CN-109824520-A A kind of preparation method of cis- -4- methyl ring amine 泰州精英化成医药科技有限公司 2019-05-31 CN claimed
CN-109824520-B Preparation method of cis-4-methylcyclohexylamine 苏州海犇药业有限公司 2021-07-23 CN disclosed
CN-109824520-A A kind of preparation method of cis- -4- methyl ring amine 泰州精英化成医药科技有限公司 2019-05-31 CN disclosed