Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27948144 | 0.82 | PDCD1 (0.43) | PDCD1CD274 | |
| SCHEMBL27641384 | 0.81 | PDCD1 (0.42) | PDCD1CD274 | |
| SCHEMBL11246005 | 0.80 | SIGMAR1 (0.55) | TAAR1HTR7KDM4ESIGMAR1LSS | |
| Hydrochloric Acid SCHEMBL9952490 | 0.79 | SIGMAR1 (0.53) | TAAR1HTR7KDM4ESIGMAR1LSS | |
| SCHEMBL7260002 | 0.78 | TAAR1 (0.78) | TAAR1SLC6A4SIGMAR1AOC3 | |
| SCHEMBL10673191 | 0.76 | HTR7 (0.63) | HTR7KDM4ELSSADRB2ADRB1 | |
| SCHEMBL27907829 | 0.74 | PDCD1 (0.48) | PDCD1CD274 | |
| SCHEMBL6771706 | 0.74 | TAAR1 (0.60) | TAAR1HTR7KDM4EPDCD1CD274 | |
| SCHEMBL31484689 | 0.74 | LIPG (0.45) | PDCD1CD274 | |
| SCHEMBL11060982 | 0.72 | CD274 (0.61) | TAAR1HTR7KDM4EPDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008322-B | sulfonamide derivatives as BC L-2-selective apoptosis-inducing agents for the treatment of cancer and immune diseases | ABBVIE 公司 | 2018-09-04 | — | — | CN | disclosed |