SCHEMBL2823735

SCHEMBL2823735

O=C(Oc1ccc([N+](=O)[O-])cc1)c1ccccc1O

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.68
KMT2A Q03164 2/20 0.68
HPGD P15428 3/20 0.65
HSD17B10 Q99714 2/20 0.65
ALOX15 P16050 1/20 0.65
PKM P14618 1/20 0.54
KDM4E B2RXH2 3/20 0.53
GAA P10253 2/20 0.53
MAPT P10636 4/20 0.53
PPARG P37231 1/20 0.52
ALOX5 P09917 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
MAOB P27338 1/20 0.50
KCNMA1 Q12791 2/20 0.49
NR1H4 Q96RI1 1/20 0.48
HGFAC Q04756 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27633734 0.86 HPGD (0.58) ALDH1A1KMT2AHPGDHSD17B10ALOX15
SCHEMBL7614991 0.85 HPGD (0.88) ALDH1A1KMT2AHPGDHSD17B10ALOX15
SCHEMBL28491071 0.84 KMT2A (0.62) ALDH1A1KMT2AHPGDPKMKDM4E
SCHEMBL12919780 0.84 HPGD (0.59) ALDH1A1KMT2AHPGDHSD17B10ALOX15
SCHEMBL11873963 0.83 ALDH1A1 (0.55) ALDH1A1KMT2AHPGDPKMKDM4E
SCHEMBL754748 0.83 KMT2A (0.59) ALDH1A1KMT2AHPGDPKMKDM4E
SCHEMBL30258384 0.83 RAB9A (0.64) ALDH1A1KMT2AHPGDHSD17B10PKM
SCHEMBL28238437 0.83 ALDH1A1 (0.55) ALDH1A1KMT2AHPGDPKMKDM4E
SCHEMBL4256409 0.83 RAB9A (0.64) ALDH1A1KMT2AHPGDHSD17B10PKM
SCHEMBL11771353 0.82 KMT2A (0.57) ALDH1A1KMT2AHPGDHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10191398-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2019-01-29 US claimed
US-10459357-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2019-10-29 US disclosed
US-20190196346-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2019-06-27 US disclosed
US-10191398-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2019-01-29 US disclosed
US-10114302-B2 Photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2018-10-30 US disclosed
US-20170343910-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2017-11-30 US disclosed
US-20170343908-A1 PHOTOCONDUCTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2017-11-30 US disclosed
US-9753384-B2 Photoconductor, electrophotographic method, electrophotographic apparatus, and electrophotographic process cartridge RICOH COMPANY, LTD. (JP) 2017-09-05 US disclosed
US-20160327877-A1 PHOTOCONDUCTOR, ELECTROPHOTOGRAPHIC METHOD, ELECTROPHOTOGRAPHIC APPARATUS, AND ELECTROPHOTOGRAPHIC PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2016-11-10 US disclosed
EP-2157159-B1 HYDRAULIC FLUID IDEMITSU KOSAN CO (JP) 2015-12-02 EP disclosed
EP-2674473-A2 Hydraulic fluid and hydraulic system IDEMITSU KOSAN CO., LTD. (JP) 2013-12-18 EP disclosed
US-8299004-B2 Hydraulic fluid and hydraulic system IDEMITSU KOSAN CO., LTD. (JP) 2012-10-30 US disclosed
US-20100130394-A1 HYDRAULIC FLUID AND HYDRAULIC SYSTEM IDEMITSU KOSAN CO., LTD (JP) 2010-05-27 US disclosed
EP-2157159-A1 HYDRAULIC FLUID AND HYDRAULIC SYSTEM Idemitsu Kosan Co., Ltd. (JP) 2010-02-24 EP disclosed
EP-0090510-B1 O-CARBAMOYL SALICYLATES AND THEIR PREPARATION Council of Scientific and Industrial Research (IN) 1987-11-11 EP disclosed
EP-0090510-A2 O-carbamoyl salicylates and their preparation Council of Scientific and Industrial Research (IN) 1983-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100130394-A1 HYDRAULIC FLUID AND HYDRAULIC SYSTEM AQP1, AQP3, TECR ALDH1A1 4415/4885KMT2A 3044/4885HPGD 426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.