SCHEMBL4256409

SCHEMBL4256409

Nc1ccccc1C(=O)Oc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.64
ALDH1A1 P00352 7/20 0.62
KMT2A Q03164 4/20 0.62
PKM P14618 1/20 0.60
KDM4E B2RXH2 4/20 0.56
HSD17B10 Q99714 2/20 0.56
HPGD P15428 2/20 0.56
GLA P06280 1/20 0.56
GAA P10253 2/20 0.52
MAPT P10636 4/20 0.52
PPARG P37231 1/20 0.51
ALOX5 P09917 1/20 0.50
HGFAC Q04756 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.49
CFTR P13569 1/20 0.47
NPC1 O15118 3/20 0.47
MEN1 O00255 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30258384 1.00 RAB9A (0.64) RAB9AALDH1A1KMT2APKMKDM4E
SCHEMBL9861291 0.85 HSD17B10 (0.71) RAB9AALDH1A1KMT2AKDM4EHSD17B10
SCHEMBL28491071 0.83 KMT2A (0.62) ALDH1A1KMT2APKMKDM4EHPGD
SCHEMBL2823735 0.83 ALDH1A1 (0.68) ALDH1A1KMT2APKMKDM4EHSD17B10
SCHEMBL28238437 0.82 ALDH1A1 (0.55) ALDH1A1KMT2APKMKDM4EHPGD
SCHEMBL11873963 0.82 ALDH1A1 (0.55) RAB9AALDH1A1KMT2APKMKDM4E
SCHEMBL754748 0.82 KMT2A (0.59) ALDH1A1KMT2APKMKDM4EHPGD
SCHEMBL19120252 0.81 ALDH1A1 (0.54) RAB9AALDH1A1KMT2APKMKDM4E
SCHEMBL8624820 0.81 RAB9A (0.63) RAB9AALDH1A1KMT2APKMHSD17B10
SCHEMBL4452103 0.81 ALDH1A1 (0.53) RAB9AALDH1A1KMT2APKMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3947667-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2022-02-09 EP claimed
WO-2020198264-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2020-10-01 WO claimed
EP-2643340-B1 COMPOSITIONS AND METHODS FOR FUNCTIONAL GLYCOMICS UNIV EMORY (US) 2019-07-31 EP claimed
US-20090131527-A1 NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-05-21 US claimed
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP disclosed
US-20240011009-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2024-01-11 US disclosed
US-11788080-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2023-10-17 US disclosed
US-20230257727-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-08-17 US disclosed
US-20230220589-A1 POLYPEPTIDE TERMINAL BINDERS AND USES THEREOF Encodia, Inc. (US) 2023-07-13 US disclosed
EP-4127157-A1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-02-08 EP disclosed
US-20230021091-A1 MODIFIED CLEAVASES, USES THEREOF AND RELATED KITS Encodia, Inc. (US) 2023-01-19 US disclosed
US-11427814-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2022-08-30 US disclosed
EP-2643340-A2 COMPOSITIONS AND METHODS FOR FUNCTIONAL GLYCOMICS Emory University (US) 2013-10-02 EP disclosed
WO-2012071371-A2 COMPOSITIONS AND METHODS FOR FUNCTIONAL GLYCOMICS EMORY UNIVERSITY (US) 2012-05-31 WO disclosed
US-20090131527-A1 NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2009-05-21 US disclosed
EP-0633145-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1998-04-15 EP disclosed
US-5612279-A REVERSIBILITY NIPPON PAPER INDUSTRIES, LTD. (JP) 1997-03-18 US disclosed
US-5470816-A Urea developers NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-11-28 US disclosed
EP-0633145-A1 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1995-01-11 EP disclosed
US-4537718-A GLUTATHIONE JOINED BY LINKAGE GROUPS TO A SECTROSCOPIC REPORTER COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1985-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090131527-A1 NOVEL ANTHRANILIC ACID DERIVATIVES AND CHLORIDE CHANNEL BLOCKING AGENT CONTAINING THE SAME CLIC1, ASIC1, CLIC4 RAB9A 870/4885ALDH1A1 1179/4885KMT2A 2701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.