Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.52 |
| ▸ | CTSV | O60911 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28490003 | 0.89 | MAOA (0.51) | AHRCTSVCTSLBCHENPC1 | |
| SCHEMBL6592979 | 0.86 | AHR (0.66) | AHRHPGDMAPTSMN1; SMN2MEN1 | |
| SCHEMBL1727453 | 0.78 | NPC1 (0.51) | AHRCTSVCTSLNPC1RAB9A | |
| SCHEMBL9300229 | 0.78 | AHR (0.59) | AHRCTSVCTSLHPGDNPC1 | |
| SCHEMBL28003901 | 0.78 | AHR (0.63) | AHRMAPTMEN1KMT2A | |
| SCHEMBL8685679 | 0.78 | AHR (0.59) | AHRCTSVCTSLHPGDMAPT | |
| SCHEMBL6596106 | 0.75 | BCHE (0.47) | CTSVCTSLBCHEHPGDMEN1 | |
| SCHEMBL7836341 | 0.75 | MAOA (0.53) | CTSVCTSLHPGDNPC1RAB9A | |
| SCHEMBL7823266 | 0.74 | MAOA (0.52) | CTSVCTSLHPGDNPC1RAB9A | |
| SCHEMBL28863000 | 0.74 | AHR (0.54) | AHRHPGDNPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358923-A | Sophoridine pyrroles, indole derivatives and the preparation method and application thereof | 广西大学 | 2018-08-03 | — | — | CN | claimed |