Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.59 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592979 | 0.87 | AHR (0.66) | AHRMEN1KMT2ACYP1A2HPGD | |
| SCHEMBL28863000 | 0.86 | AHR (0.54) | AHRMEN1KMT2ACYP1A2HPGD | |
| SCHEMBL28003901 | 0.85 | AHR (0.63) | AHRCNR1MEN1KMT2ALMNA | |
| SCHEMBL8685679 | 0.85 | AHR (0.59) | AHRMEN1KMT2ACYP1A2HPGD | |
| SCHEMBL9299886 | 0.82 | AHR (0.60) | AHRMEN1KMT2ACYP1A2HPGD | |
| SCHEMBL1249895 | 0.79 | AHR (0.59) | AHRMEN1KMT2ACYP1A2HPGD | |
| SCHEMBL29951745 | 0.79 | AHR (0.59) | AHRMEN1KMT2ACYP1A2HPGD | |
| SCHEMBL28239180 | 0.78 | AHR (0.52) | AHRMEN1KMT2AHPGDMAPT | |
| SCHEMBL19346257 | 0.78 | AHR (0.77) | AHRMEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL2559637 | 0.76 | PTGS2 (0.55) | AHRCYP1A2HPGDCYP2C19TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623138-A1 | NEW ADENOSINE DERIVATIVES, PREPARATION METHODS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. | UNION PHARMA SCIENT APPL (FR) | 1994-11-09 | — | — | EP | disclosed |