Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 6/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6592979 | 0.87 | AHR (0.66) | AHRALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL28003901 | 0.85 | AHR (0.63) | AHRPOLBLMNAMETALDH1A1 | |
| SCHEMBL9300229 | 0.85 | AHR (0.59) | AHRPOLBLMNACTSVCTSL | |
| SCHEMBL28239180 | 0.78 | AHR (0.52) | AHRCTSVCTSLSMN1; SMN2MEN1 | |
| SCHEMBL28863000 | 0.77 | AHR (0.54) | AHRPOLBALDH1A1KDM4EMEN1 | |
| SCHEMBL2062029 | 0.76 | PTGS2 (0.54) | AHRPOLBCTSVCTSLKDM4E | |
| SCHEMBL28804759 | 0.76 | POLB (0.48) | POLBLMNAMETCTSVCTSL | |
| SCHEMBL1249895 | 0.76 | AHR (0.59) | AHRALDH1A1HTTMEN1KMT2A | |
| SCHEMBL9274962 | 0.76 | AHR (0.59) | AHRPOLBLMNAALDH1A1HTT | |
| SCHEMBL29951745 | 0.76 | AHR (0.59) | AHRALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |