Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 5/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300229 | 0.86 | AHR (0.59) | AHRIMPDH2CYP1A2CYP2C19MEN1 | |
| SCHEMBL6592979 | 0.85 | AHR (0.66) | AHRIMPDH2CYP1A2CYP2C19MEN1 | |
| SCHEMBL9299886 | 0.80 | AHR (0.60) | AHRCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL28490003 | 0.79 | MAOA (0.51) | AHRMEN1KMT2ANPC1 | |
| SCHEMBL8685679 | 0.77 | AHR (0.59) | AHRCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL28003901 | 0.77 | AHR (0.63) | AHRMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL19346257 | 0.76 | AHR (0.77) | AHRMEN1KMT2ACYP3A4TDP1 | |
| SCHEMBL1249895 | 0.75 | AHR (0.59) | AHRCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL29951745 | 0.75 | AHR (0.59) | AHRCYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL28239180 | 0.74 | AHR (0.52) | AHRMEN1KMT2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358923-A | Sophoridine pyrroles, indole derivatives and the preparation method and application thereof | 广西大学 | 2018-08-03 | — | — | CN | claimed |