Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15240100 | 0.79 | ALOX15 (0.33) | — | |
| SCHEMBL3454973 | 0.79 | GAA (0.30) | — | |
| SCHEMBL15352836 | 0.73 | CA1 (0.31) | CA1CA2CA9 | |
| SCHEMBL21295188 | 0.73 | LMNA (0.42) | — | |
| SCHEMBL28706010 | 0.72 | APP (0.30) | — | |
| SCHEMBL27655474 | 0.71 | ALOX15 (0.39) | CA1CA2 | |
| SCHEMBL29224827 | 0.70 | — | — | |
| SCHEMBL27964166 | 0.70 | FAAH (0.42) | — | |
| SCHEMBL2135666 | 0.70 | CA1 (0.33) | CA1 | |
| SCHEMBL15352840 | 0.69 | TXNRD1 (0.31) | CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053742-B | Novel tricyclic compounds | ABBVIE 公司 | 2021-06-15 | — | — | CN | disclosed |
| CN-109053742-A | New tricyclic compound | ABBVIE 公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108774237-A | New tricyclic compound | ABBVIE 公司 | 2018-11-09 | — | — | CN | disclosed |
| CN-104370909-B | Tricyclic compound | ABBVIE 公司 | 2018-09-11 | — | — | CN | disclosed |