Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27652936 | 0.83 | APP (0.39) | APP | |
| SCHEMBL15240100 | 0.81 | ALOX15 (0.33) | — | |
| SCHEMBL21295188 | 0.79 | LMNA (0.42) | APP | |
| SCHEMBL29153970 | 0.77 | CES2 (0.36) | — | |
| SCHEMBL4431954 | 0.77 | CA2 (0.41) | — | |
| Water SCHEMBL4601019 | 0.77 | CES2 (0.36) | — | |
| SCHEMBL9409054 | 0.75 | CA2 (0.39) | — | |
| Hydrogen Sulfide SCHEMBL27994029 | 0.75 | CA2 (0.39) | — | |
| SCHEMBL27857813 | 0.75 | NAAA (0.31) | — | |
| SCHEMBL28167848 | 0.75 | CA2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026073-A | Quinazolin-4-one derivatives for the treatment of BRAF related diseases and disorders | ARRAY生物制药公司 | 2022-02-08 | — | — | CN | disclosed |