Carbazole

Carbazole

SCHEMBL28240491

CC(SC(O)=S)c1ccccc1.c1ccc2c(c1)[nH]c1ccccc12

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.46
ALDH1A1 P00352 2/20 0.45
HSD17B10 Q99714 2/20 0.45
GPR3 P46089 1/20 0.45
KMT2A Q03164 3/20 0.42
MEN1 O00255 2/20 0.42
POLB P06746 1/20 0.42
GABRA1 P14867 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GABRA4 P48169 1/20 0.40
GABRA6 Q16445 1/20 0.40
AHR P35869 1/20 0.40
VDR P11473 2/20 0.39
CCNB2 O95067 1/20 0.39
CDK1 P06493 1/20 0.39
CCNB1 P14635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6535241 0.84 ADRA2C (0.40) ALDH1A1HSD17B10KMT2AMEN1LMNA
SCHEMBL11443376 0.73 ADRA2C (0.40) ALDH1A1HSD17B10KMT2AMEN1LMNA
Carbazole SCHEMBL29148121 0.72 ALDH1A1 (0.70) KIF11ALDH1A1HSD17B10GPR3KMT2A
SCHEMBL12590975 0.71 ADRA2C (0.39) ALDH1A1HSD17B10KMT2ALMNAKDM4E
Carbazole SCHEMBL28214855 0.70 ALDH1A1 (0.67) KIF11ALDH1A1HSD17B10GPR3KMT2A
Carbazole SCHEMBL28048441 0.70 ALDH1A1 (0.82) KIF11ALDH1A1HSD17B10GPR3KMT2A
SCHEMBL122869 0.70 ADRA2C (0.39) ALDH1A1HSD17B10KMT2AMEN1LMNA
SCHEMBL11443377 0.70 KMT2A (0.41) ALDH1A1HSD17B10KMT2ALMNAKDM4E
SCHEMBL28351657 0.70 ADRA2A (0.42) ALDH1A1KMT2ALMNAKDM4E
SCHEMBL28351658 0.70 ADRA2A (0.42) ALDH1A1KMT2ALMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108586963-A A kind of application of ionic liquid block polymer in supercritical carbon dioxide microporous foam 台州学院 2018-09-28 CN disclosed
CN-108503746-A A kind of preparation and application of water solubility 3D printing backing material 台州学院 2018-09-07 CN disclosed