SCHEMBL28243735

SCHEMBL28243735

C=CC(=O)Oc1c(C)cccc1-c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
BACE1 P56817 1/20 0.39
MYC P01106 1/20 0.38
FGFR1 P11362 1/20 0.38
FGFR2 P21802 1/20 0.38
FGFR4 P22455 1/20 0.38
FGFR3 P22607 1/20 0.38
NPC1 O15118 1/20 0.37
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
TYMS P04818 1/20 0.37
SCN8A Q9UQD0 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27619078 0.88 MEN1 (0.36) SMN1; SMN2L3MBTL1MEN1KMT2AKDM4E
SCHEMBL27779774 0.86 HSD17B1 (0.38) MEN1KMT2ATYMS
SCHEMBL25565205 0.84 L3MBTL1 (0.47) SMN1; SMN2L3MBTL1MEN1KMT2AKDM4E
SCHEMBL27726412 0.83 TYMS (0.44) SMN1; SMN2L3MBTL1KMT2AKDM4EALDH1A1
SCHEMBL28195023 0.82 FABP3 (0.43) L3MBTL1MEN1KMT2AKDM4EALDH1A1
SCHEMBL180120 0.82 SMN1; SMN2 (0.47) SMN1; SMN2L3MBTL1MEN1KMT2AKDM4E
Methane SCHEMBL29047002 0.82 TYMS (0.43) SMN1; SMN2L3MBTL1KMT2AKDM4EALDH1A1
SCHEMBL14689965 0.82 HNF4A (0.50) SMN1; SMN2L3MBTL1MEN1KMT2AKDM4E
Hydrogen Sulfide SCHEMBL27805768 0.81 L3MBTL1 (0.36) SMN1; SMN2L3MBTL1BACE1THRATHRB
SCHEMBL28716844 0.78 ALDH1A1 (0.44) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699184-B (methyl) acrylic-based compositions, coating and solidified body comprising being somebody's turn to do (methyl) acrylic-based compositions 三菱瓦斯化学株式会社 2019-08-09 CN disclosed
CN-108699184-A (methyl) acrylic-based compositions include the coating and firming body for being somebody's turn to do (methyl) acrylic-based compositions 三菱瓦斯化学株式会社 2018-10-23 CN disclosed
CN-108603953-A Light diffusing agent, light-diffusing resin composition and formed body 三菱瓦斯化学株式会社 2018-09-28 CN disclosed