SCHEMBL28244012

SCHEMBL28244012

CCOC(=O)C(C=CC(N)C(C)(C)C)C(C)=O

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
ALDH1A1 P00352 2/20 0.34
METAP2 P50579 2/20 0.34
METAP1 P53582 2/20 0.34
LMNA P02545 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ALOX15 P16050 1/20 0.32
GAA P10253 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CPB2 Q96IY4 1/20 0.31
GLO1 Q04760 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28116044 0.73 ALDH1A1 (0.39) CYP2D6CYP2C9CYP2C19ALDH1A1LMNA
SCHEMBL6070239 0.70 ALDH1A1 (0.44) CYP2D6CYP2C9CYP2C19ALDH1A1LMNA
SCHEMBL9620431 0.69 GLO1 (0.36) CYP2D6CYP2C9CYP2C19ALDH1A1LMNA
SCHEMBL9620433 0.69 GLO1 (0.36) CYP2D6CYP2C9CYP2C19ALDH1A1LMNA
SCHEMBL15046951 0.69 ALDH1A1 (0.42) CYP2D6CYP2C9CYP2C19ALDH1A1LMNA
SCHEMBL18431955 0.68 FBP1 (0.36) CYP2C9CYP2C19ALDH1A1LMNAHSD17B10
SCHEMBL4079531 0.68 ALOX15 (0.44) CYP2D6CYP2C9CYP2C19ALDH1A1METAP2
SCHEMBL8004357 0.68 ALOX15 (0.44) CYP2D6CYP2C9CYP2C19ALDH1A1METAP2
SCHEMBL14769893 0.68 ALOX15 (0.44) CYP2D6CYP2C9CYP2C19ALDH1A1METAP2
SCHEMBL26783311 0.66 ALDH1A1 (0.40) CYP2D6CYP2C9CYP2C19ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473493-A Functionalized valeric acid for influenza infection 爱尔兰詹森科学公司 2018-08-31 CN disclosed