Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28247538 | 0.72 | KDM4E (0.41) | KMT2AHPGDTSHRNPSR1ALDH1A1 | |
| SCHEMBL19170774 | 0.69 | ALDH1A1 (0.51) | NCF1KMT2AHPGDTSHRNPSR1 | |
| SCHEMBL15426751 | 0.69 | FAAH (0.46) | NCF1POLBHPGDTSHRALDH1A1 | |
| SCHEMBL11339430 | 0.67 | USP2 (0.45) | HPGDTSHRALDH1A1GAASMN1; SMN2 | |
| SCHEMBL19176232 | 0.66 | ALDH1A1 (0.49) | KMT2APOLBHPGDTSHRNPSR1 | |
| SCHEMBL24801822 | 0.66 | SMN1; SMN2 (0.42) | NCF1POLBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL10310081 | 0.66 | ALDH1A1 (0.53) | KMT2AALDH1A1SMN1; SMN2MEN1HSD17B10 | |
| SCHEMBL10310114 | 0.66 | ALDH1A1 (0.49) | KMT2AHPGDALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL25928428 | 0.66 | ALDH1A1 (0.39) | KMT2APOLBHPGDTSHRALDH1A1 | |
| SCHEMBL30168920 | 0.65 | MAPT (0.54) | KMT2APOLBHPGDTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108690043-B | Quinoline derivatives and its preparation method and application | 东莞东阳光科研发有限公司 | 2019-10-18 | — | — | CN | disclosed |
| CN-108690043-A | Quinoline derivatives and its preparation method and application | 东莞东阳光科研发有限公司 | 2018-10-23 | — | — | CN | disclosed |