Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 2/20 | 0.52 |
| ▸ | NCK1 | P16333 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.39 |
| ▸ | PLAU | P00749 | 4/20 | 0.38 |
| ▸ | PLG | P00747 | 3/20 | 0.38 |
| ▸ | PLAT | P00750 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3296780 | 0.83 | CYP1A2 (0.53) | NCK1BACE1CYP1A2PSMB5ALDH1A1 | |
| SCHEMBL27802880 | 0.79 | MAOA (0.50) | KARS1NOS3NOS1NOS2CDK8 | |
| SCHEMBL29692924 | 0.78 | PSMB5 (0.57) | NCK1BACE1CYP1A2PSMB5ALDH1A1 | |
| SCHEMBL8830006 | 0.78 | PSMB5 (0.57) | NCK1BACE1CYP1A2PSMB5ALDH1A1 | |
| SCHEMBL27761556 | 0.78 | NOS3 (0.61) | KARS1NOS3NOS1NOS2CDK8 | |
| SCHEMBL12547143 | 0.76 | CYP3A4 (0.50) | KARS1NOS3NOS1NOS2CDK8 | |
| SCHEMBL21537318 | 0.75 | KDM4E (0.53) | KARS1NCK1BACE1MAP4K4PLAU | |
| SCHEMBL10147842 | 0.74 | CYP1A2 (0.59) | NCK1BACE1CYP1A2PSMB5ALDH1A1 | |
| SCHEMBL14269748 | 0.74 | CTSS (0.45) | NCK1BACE1CYP1A2 | |
| SCHEMBL23247265 | 0.74 | CYP1A2 (0.68) | NCK1BACE1CYP1A2PSMB5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558753-A | The method that carbostyril compound is prepared as CO source of releases using iron pentacarbonyl | 陕西师范大学 | 2018-09-21 | — | — | CN | disclosed |