Acetic Acid Phenyl Ester

Acetic Acid Phenyl Ester

SCHEMBL28249394

CC(=O)Oc1ccccc1.CC(C)(C)C(=O)OCCc1ccccc1

nearest known ligand 0.49

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
ELANE P08246 3/20 0.47
GAA P10253 2/20 0.45
ALOX5 P09917 1/20 0.44
HCAR2 Q8TDS4 1/20 0.43
KMT2A Q03164 1/20 0.43
PTGS2 P35354 1/20 0.43
ALDH1A1 P00352 3/20 0.42
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
HSP90AA1 P07900 1/20 0.42
MAPT P10636 1/20 0.42
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP9 P14780 1/20 0.42
MMP12 P39900 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290872 0.88 HCAR2 (0.53) NPC1RAB9ASMN1; SMN2ALOX5HCAR2
SCHEMBL8663566 0.79 LMNA (0.62) NPC1RAB9ASMN1; SMN2KMT2AALDH1A1
SCHEMBL3961218 0.77 FFAR1 (0.64) NPC1RAB9ASMN1; SMN2ELANEGAA
SCHEMBL3935097 0.77 LMNA (0.56) NPC1RAB9ASMN1; SMN2MAPTTDP1
SCHEMBL12389249 0.77 THRB (0.56) NPC1RAB9ASMN1; SMN2KMT2AALDH1A1
SCHEMBL717987 0.76 NPC1 (0.65) NPC1RAB9ASMN1; SMN2ELANEGAA
SCHEMBL111422 0.76 ALDH1A1 (0.64) NPC1RAB9ASMN1; SMN2ALOX5HCAR2
Acetic Acid Phenyl Ester SCHEMBL20524448 0.76 ELANE (0.60) ELANEGAAKMT2APTGS2ALDH1A1
SCHEMBL4351183 0.76 ALDH1A1 (0.64) NPC1RAB9ASMN1; SMN2ALOX5HCAR2
Benzene SCHEMBL19304565 0.76 ALDH1A1 (0.64) NPC1RAB9ASMN1; SMN2ALOX5HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108601958-A Pro-perfume compositions 爱客多有限公司 2018-09-28 CN disclosed