SCHEMBL28249652

SCHEMBL28249652

C#CC(OCC(C)(C)O)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 2/20 0.35
SLC6A4 P31645 3/20 0.33
SLC6A3 Q01959 3/20 0.33
SLC6A2 P23975 1/20 0.33
LMNA P02545 2/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA2C P18825 1/20 0.32
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP3A4 P08684 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28249650 1.00 RIPK1 (0.35) RIPK1SLC6A4SLC6A3SLC6A2LMNA
SCHEMBL28250324 0.84 RIPK1 (0.33) RIPK1SLC6A4SLC6A3SLC6A2LMNA
SCHEMBL28250323 0.84 RIPK1 (0.33) RIPK1SLC6A4SLC6A3SLC6A2LMNA
SCHEMBL5243353 0.77 L3MBTL1 (0.39) SLC6A4SLC6A3SLC6A2LMNAL3MBTL1
SCHEMBL28249657 0.75 LMNA (0.46) LMNAL3MBTL1ADRA2AADRA2CHIF1A
SCHEMBL28249653 0.75 LMNA (0.46) LMNAL3MBTL1ADRA2AADRA2CHIF1A
SCHEMBL28249655 0.75 LMNA (0.46) LMNAL3MBTL1ADRA2AADRA2CHIF1A
SCHEMBL25207508 0.74 ALDH1A1 (0.39) SLC6A4SLC6A3SLC6A2LMNAADRA2A
SCHEMBL28865641 0.74 ALDH1A1 (0.39) SLC6A4SLC6A3SLC6A2LMNAADRA2A
SCHEMBL77245 0.73 DPP4 (0.36) LMNAADRA2AADRA2CHIF1AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108722484-B Composition for preparing propargyl ether 四川大学 2021-04-27 CN disclosed
CN-108722484-A A kind of composition preparing propargyl ether 四川大学 2018-11-02 CN disclosed