Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ACACA | Q13085 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 11/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 2/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632837 | 0.85 | RIPK1 (0.40) | RIPK1ACACBACACA | |
| SCHEMBL28158302 | 0.78 | RIPK1 (0.43) | RIPK1ACACBACACAEPHX2 | |
| SCHEMBL16632685 | 0.76 | CNR2 (0.38) | RIPK1ALDH1A1 | |
| SCHEMBL14294137 | 0.70 | BLM (0.62) | RIPK1EPHX2ALDH1A1 | |
| SCHEMBL18228641 | 0.69 | GAA (0.58) | RIPK1EPHX2ALDH1A1 | |
| SCHEMBL18321777 | 0.68 | MGLL (0.60) | EPHX2ALDH1A1 | |
| SCHEMBL28051082 | 0.68 | HSD11B1 (0.68) | ALDH1A1 | |
| SCHEMBL18909217 | 0.67 | HTT (0.62) | RIPK1ACACBACACAEPHX2ALDH1A1 | |
| SCHEMBL12436953 | 0.67 | EPHX2 (0.50) | RIPK1EPHX2ALDH1A1 | |
| SCHEMBL4259604 | 0.67 | L3MBTL1 (0.54) | RIPK1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829294-B | The quinolyl conditioning agent of ROR- γ-T being connect with methylene | 詹森药业有限公司 | 2018-11-09 | — | — | CN | disclosed |