Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.37 |
| ▸ | CA9 | Q16790 | 5/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3846804 | 0.76 | MAPT (0.42) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL920851 | 0.75 | MAPT (0.41) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9230402 | 0.75 | ALDH1A1 (0.42) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL15066907 | 0.75 | MAPT (0.41) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL16057644 | 0.73 | LMNA (0.38) | MAPTLMNAALDH1A1RAB9A | |
| SCHEMBL22987 | 0.73 | CYP3A4 (0.38) | MAPTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL9834426 | 0.71 | LMNA (0.39) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9738774 | 0.71 | MAPT (0.42) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL482465 | 0.69 | CA12 (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7557594 | 0.69 | NQO1 (0.38) | MAPTMEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864160-A | The preparation method of boron-containing small molecules | 苏州旺山旺水生物医药有限公司 | 2018-11-23 | — | — | CN | disclosed |