SCHEMBL2825335

SCHEMBL2825335

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nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2825343 1.00 TSHR (0.33) TSHR
SCHEMBL2825340 1.00 TSHR (0.33) TSHR
SCHEMBL3029519 0.84 TSHR (0.38) TSHR
SCHEMBL31470910 0.82 ADH1B (0.40) TSHR
SCHEMBL3034082 0.79 TSHR (0.36) TSHR
SCHEMBL3035559 0.79 FOLH1 (0.31)
SCHEMBL27110 0.78
SCHEMBL3044336 0.76 CTSK (0.33) TSHR
SCHEMBL31365425 0.75 TSHR (0.53) TSHR
SCHEMBL29197507 0.75 TSHR (0.53) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220386582-A1 METHOD AND DEVICE TO TRAP ACARIDS DOMOBIOS (BE) 2022-12-08 US disclosed
US-20210161130-A1 COMPOSITIONS FOR ATTRACTING PESTS AND USES THEREOF DOMOBIOS (BE) 2021-06-03 US disclosed
US-20200344991-A1 METHOD AND DEVICE TO TRAP ACARIDS DOMOBIOS (BE) 2020-11-05 US disclosed
EP-3253203-B1 METHOD AND DEVICE TO TRAP ACARIDS DOMOBIOS (BE) 2020-10-28 EP disclosed
US-20180027793-A1 METHOD AND DEVICE TO TRAP ACARIDS DOMOBIOS (BE) 2018-02-01 US disclosed
WO-2016124566-A1 METHOD AND DEVICE TO TRAP ACARIDS DOMOBIOS (BE) 2016-08-11 WO disclosed
US-8715704-B2 Lure LONDON SCHOOL OF HYGIENE & TROPICAL MEDICINE (GB) 2014-05-06 US disclosed
US-20100310499-A1 LURE LONDON SCHOOL OF HYGIENE & TROPICAL MEDICINE (GB) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100310499-A1 LURE LAGE3, ELANE, DDT TSHR 2189/4885
US-20210161130-A1 COMPOSITIONS FOR ATTRACTING PESTS AND USES THEREOF ACAT1, ATL3, NISCH TSHR 4469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.