Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 4/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469163 | 0.87 | CASP3 (0.55) | KMT2AGAAMAPK1MEN1POLB | |
| SCHEMBL3469175 | 0.79 | GAA (0.56) | KMT2AGAAMAPK1MEN1POLB | |
| SCHEMBL3478684 | 0.76 | MAPK1 (0.52) | KMT2AGAAMAPK1MEN1POLB | |
| SCHEMBL2780829 | 0.76 | GAA (0.59) | KMT2AGAAMAPK1MEN1POLB | |
| SCHEMBL14563326 | 0.76 | CASP3 (0.46) | KMT2AGAAMAPK1MEN1POLB | |
| SCHEMBL3472577 | 0.75 | OPRM1 (0.38) | KMT2AGAAMAPK1MEN1POLB | |
| SCHEMBL3472575 | 0.75 | OPRM1 (0.51) | KMT2AGAAMAPK1MEN1POLB | |
| SCHEMBL2825338 | 0.74 | MAPK1 (0.54) | KMT2AGAAMAPK1MEN1POLB | |
| SCHEMBL13273674 | 0.74 | CNR2 (0.44) | KMT2AMEN1POLBCASP3CASP7 | |
| SCHEMBL13196452 | 0.74 | GAA (0.50) | KMT2AGAAMAPK1MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077839-A1 | SUBSTITUTED OXINDOL CB2 AGONISTS FOR PAIN TREATMENT | WYETH LLC (FORMERLY KNOWN AS WYETH) (US) | 2010-07-08 | — | — | WO | disclosed |