SCHEMBL28256353

SCHEMBL28256353

C[N+](C)(Cc1ccccc1)c1ccccc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
KDM4E B2RXH2 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
DNM1 Q05193 2/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
TP53 P04637 2/20 0.37
MAPK1 P28482 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HTT P42858 2/20 0.36
TSHR P16473 2/20 0.35
LMNA P02545 2/20 0.35
SIGMAR1 Q99720 1/20 0.34
TAAR1 Q96RJ0 3/20 0.33
PTPN7 P35236 1/20 0.33
DUSP3 P51452 1/20 0.33
PTPN5 P54829 1/20 0.33
PTPN11 Q06124 1/20 0.33
CALM1 P0DP23 1/20 0.32
CHRNB2 P17787 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564456 0.78 ALDH1A1 (0.50) ALDH1A1KDM4ETDP1DNM1MEN1
SCHEMBL4649848 0.76 ALDH1A1 (0.48) ALDH1A1KDM4ETDP1DNM1MEN1
Hydrochloric Acid SCHEMBL31362231 0.76 ALDH1A1 (0.54) ALDH1A1KDM4ETDP1DNM1MEN1
Bromide SCHEMBL5127809 0.74 ALDH1A1 (0.47) ALDH1A1KDM4ETDP1DNM1MEN1
Bromide SCHEMBL11060577 0.74 ALDH1A1 (0.47) ALDH1A1KDM4ETDP1DNM1MEN1
SCHEMBL28423034 0.74 KDM4E (0.47) ALDH1A1KDM4ETDP1DNM1MEN1
SCHEMBL28021011 0.73 ACHE (0.57) ALDH1A1KDM4ETDP1MEN1KMT2A
SCHEMBL6624834 0.73 ALDH1A1 (0.45) ALDH1A1KDM4ETDP1DNM1MEN1
SCHEMBL565108 0.72 KDM4E (0.58) ALDH1A1KDM4ETDP1DNM1MEN1
SCHEMBL27977449 0.71 TSHR (0.47) ALDH1A1SMN1; SMN2TSHRLMNATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109055743-A A kind of extracts composition and its application 中国科学院上海有机化学研究所 2018-12-21 CN claimed
CN-108950247-A A kind of extraction system and its application 中国科学院上海有机化学研究所 2018-12-07 CN claimed
CN-108754141-A A kind of extraction organic phase and its application 中国科学院上海有机化学研究所 2018-11-06 CN claimed
CN-108103317-A A kind of method that lithium is recycled from waste liquid containing lithium 中国科学院上海有机化学研究所 2018-06-01 CN claimed
CN-109055743-A A kind of extracts composition and its application 中国科学院上海有机化学研究所 2018-12-21 CN disclosed
CN-108950247-A A kind of extraction system and its application 中国科学院上海有机化学研究所 2018-12-07 CN disclosed
CN-108754141-A A kind of extraction organic phase and its application 中国科学院上海有机化学研究所 2018-11-06 CN disclosed
CN-108103317-A A kind of method that lithium is recycled from waste liquid containing lithium 中国科学院上海有机化学研究所 2018-06-01 CN disclosed