Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL564456 | 0.98 | ALDH1A1 (0.50) | ALDH1A1KDM4ETDP1SMN1; SMN2MEN1 | |
| SCHEMBL4649332 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KDM4ETDP1SMN1; SMN2MEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL565377 | 0.81 | GPR3 (0.36) | ALDH1A1KDM4ETDP1ACHEHPGD | |
| SCHEMBL31413514 | 0.80 | LTA4H (0.46) | ALDH1A1KDM4ETDP1SMN1; SMN2HTT | |
| Bromide SCHEMBL5117868 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4ETDP1SMN1; SMN2MEN1 | |
| Fluoride SCHEMBL26928814 | 0.79 | LTA4H (0.44) | ALDH1A1KDM4ETDP1SMN1; SMN2HTT | |
| Fluoride Ion SCHEMBL26928818 | 0.79 | LTA4H (0.44) | ALDH1A1KDM4ETDP1SMN1; SMN2HTT | |
| SCHEMBL28423034 | 0.78 | KDM4E (0.47) | ALDH1A1KDM4ETDP1SMN1; SMN2MEN1 | |
| O-Xylene SCHEMBL27528874 | 0.77 | KDM4E (0.82) | ALDH1A1KDM4ETDP1SMN1; SMN2MEN1 | |
| SCHEMBL28256353 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KDM4ETDP1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119053460-A | Tyre for vehicle wheels | 倍耐力轮胎股份公司 | 2024-11-29 | — | — | CN | disclosed |