Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451016 | 0.78 | PSIP1 (0.56) | CA2KMT2AMEN1HSD11B1PSIP1 | |
| SCHEMBL2536096 | 0.78 | PSIP1 (0.56) | CA2KMT2ASMN1; SMN2HSD11B1PSIP1 | |
| SCHEMBL28077902 | 0.73 | TP53 (0.44) | CA2KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL27829 | 0.70 | SMN1; SMN2 (0.40) | CA2SMN1; SMN2ALDH1A1CA1 | |
| SCHEMBL17803840 | 0.69 | ALDH1A1 (0.64) | CA2KMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL1908884 | 0.68 | PSIP1 (0.52) | CA2KMT2AMEN1HSD11B1PSIP1 | |
| SCHEMBL15577883 | 0.68 | PLCG1 (0.55) | CA2KMT2AMEN1LMNAHSD11B1 | |
| SCHEMBL2535633 | 0.68 | CRBN (0.41) | SMN1; SMN2PSIP1MAPTALDH1A1 | |
| SCHEMBL1271000 | 0.68 | CA2 (0.54) | CA2KMT2AMEN1HSD11B1ALDH1A1 | |
| SCHEMBL13650701 | 0.67 | CA2 (0.49) | CA2KMT2AMEN1LMNAHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864076-A | glucosylceramide synthase inhibitors | 建新公司 | 2018-11-23 | — | — | CN | disclosed |