Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2819374 | 0.90 | TBXAS1 (0.42) | L3MBTL1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2821944 | 0.89 | LMNA (0.42) | L3MBTL1MAPTRAB9AKMT2AHSD17B10 | |
| SCHEMBL2819390 | 0.88 | THRB (0.38) | L3MBTL1MAPTNPC1RAB9AKLKB1 | |
| SCHEMBL2823014 | 0.85 | KLKB1 (0.39) | MAPTSMN1; SMN2KLKB1MEN1KMT2A | |
| SCHEMBL2819683 | 0.85 | KLKB1 (0.37) | L3MBTL1MAPTSMN1; SMN2RAB9AKLKB1 | |
| SCHEMBL2822731 | 0.82 | RARA (0.36) | MAPTSMN1; SMN2KLKB1CYP1A2CYP3A4 | |
| SCHEMBL2824753 | 0.81 | TBXAS1 (0.43) | L3MBTL1MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL2819508 | 0.80 | TSHR (0.36) | L3MBTL1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL2819470 | 0.79 | L3MBTL1 (0.47) | L3MBTL1MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2822380 | 0.79 | LMNA (0.41) | L3MBTL1MAPTRAB9AKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | MPM ASSET MANAGEMENT INVESTORS 2002 BVIII LLC | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184815-A1 | AGONISTS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR-ALPHA | PPARA, PPARD, PPARG | L3MBTL1 4855/4885MAPT 4229/4885SMN1; SMN2 4788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.