Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 3/20 | 0.43 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28866664 | 0.85 | PTPN1 (0.52) | RAB9ASMN1; SMN2TP53MAPK14MEN1 | |
| SCHEMBL28259973 | 0.84 | MAPT (0.52) | RAB9ASMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL28261356 | 0.84 | MAPT (0.49) | RAB9ASMN1; SMN2TP53NPSR1MAPK14 | |
| SCHEMBL27972367 | 0.83 | SMN1; SMN2 (0.56) | RAB9ASMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL27972591 | 0.82 | MAPK14 (0.39) | RAB9ASMN1; SMN2TP53MAPK14MEN1 | |
| SCHEMBL27972362 | 0.82 | LMNA (0.54) | RAB9ANPSR1MAPK14MEN1KMT2A | |
| SCHEMBL28259950 | 0.80 | NPC1 (0.51) | RAB9ASMN1; SMN2TSHRMEN1KMT2A | |
| SCHEMBL28259952 | 0.80 | PTPN1 (0.52) | SMN1; SMN2MAPK14PARP1 | |
| SCHEMBL27972606 | 0.80 | KDM4E (0.51) | RAB9ASMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL27972271 | 0.79 | RAB9A (0.53) | RAB9ASMN1; SMN2TP53NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863959-B | P2X4 receptor antagonists | 日本化学药品株式会社 | 2021-11-30 | — | — | CN | disclosed |
| CN-111333588-A | P2X4 receptor antagonists | 日本化学药品株式会社 | 2020-06-26 | — | — | CN | disclosed |
| CN-110483423-A | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO | 2019-11-22 | — | — | CN | disclosed |
| CN-108863959-A | P2X4 RECEPTOR ANTAGONIST | 日本化学药品株式会社 | 2018-11-23 | — | — | CN | disclosed |