Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259952 | 0.95 | PTPN1 (0.52) | PTPN1MAPK14KDM4ESIRT1POLB | |
| SCHEMBL27972606 | 0.90 | KDM4E (0.51) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL27972353 | 0.87 | NAMPT (0.51) | NPC1RAB9AKDM4ESMN1; SMN2TP53 | |
| SCHEMBL27972271 | 0.87 | RAB9A (0.53) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL27972362 | 0.85 | LMNA (0.54) | PTPN1MAPK14RAB9AMEN1KMT2A | |
| SCHEMBL28261356 | 0.85 | MAPT (0.49) | MAPK14NPC1RAB9AKDM4ESIRT1 | |
| SCHEMBL28259957 | 0.85 | ADCY1 (0.43) | MAPK14NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28426457 | 0.85 | CHRNB2 (0.43) | MEN1KMT2APOLBSMN1; SMN2GAA | |
| SCHEMBL28279915 | 0.84 | MEN1 (0.49) | MEN1KMT2APOLBTP53GAA | |
| SCHEMBL27972549 | 0.84 | SMO (0.53) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483423-A | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO | 2019-11-22 | — | — | CN | disclosed |
| CN-108863959-A | P2X4 RECEPTOR ANTAGONIST | 日本化学药品株式会社 | 2018-11-23 | — | — | CN | disclosed |