Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | CEPT1 | Q9Y6K0 | 2/20 | 0.52 |
| ▸ | CETP | P11597 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259972 | 0.86 | NPC1 (0.47) | MEN1KMT2AHTTMAPTALDH1A1 | |
| SCHEMBL28423745 | 0.80 | LMNA (0.50) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL28391961 | 0.79 | RAB9A (0.47) | MEN1KMT2AHTTMAPTALDH1A1 | |
| SCHEMBL27972580 | 0.78 | BCHE (0.49) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL27972608 | 0.77 | KCNK3 (0.50) | KMT2AMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL27972293 | 0.76 | RAB9A (0.54) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL27972631 | 0.76 | MAPT (0.51) | MEN1KMT2AHTTMAPTNPC1 | |
| SCHEMBL27972550 | 0.76 | GRM1 (0.43) | MAPTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27972283 | 0.76 | MEN1 (0.41) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL27972318 | 0.75 | PTPN1 (0.48) | MEN1KMT2AMAPTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483423-A | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO | 2019-11-22 | — | — | CN | disclosed |
| CN-108863959-A | P2X4 RECEPTOR ANTAGONIST | 日本化学药品株式会社 | 2018-11-23 | — | — | CN | disclosed |