Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28813725 | 0.88 | GRM1 (0.46) | GRM1KDM4ETRPV1GRM4 | |
| SCHEMBL27972621 | 0.86 | NPC1 (0.42) | KDM4ETRPV1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28813208 | 0.85 | KDM4E (0.35) | GRM1KDM4ETRPV1GRM4NPC1 | |
| SCHEMBL27972308 | 0.82 | MEN1 (0.50) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL27972300 | 0.80 | LMNA (0.38) | KDM4EKITNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27972606 | 0.80 | KDM4E (0.51) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL27972271 | 0.79 | RAB9A (0.53) | KDM4ENPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL28391961 | 0.79 | RAB9A (0.47) | KDM4ERAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL28259971 | 0.79 | ROCK2 (0.48) | GRM1KDM4EGRM4NPC1RAB9A | |
| SCHEMBL28866664 | 0.78 | PTPN1 (0.52) | KDM4EKITNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104066724-A | P2X4 receptor antagonists | NIPPON CHEMIPHAR CO | 2014-09-24 | — | — | CN | disclosed |