Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23615876 | 0.89 | TAAR1 (0.38) | MPOSLC6A4HTR2A | |
| SCHEMBL28306582 | 0.79 | DAO (0.33) | HTR2A | |
| SCHEMBL18617143 | 0.75 | — | — | |
| SCHEMBL27506183 | 0.71 | TAAR1 (0.40) | MPOSLC6A4HTR2A | |
| SCHEMBL13488450 | 0.71 | IFNAR1 (0.33) | SLC6A4HTR2A | |
| SCHEMBL25079074 | 0.69 | DRD2 (0.34) | — | |
| SCHEMBL30887044 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL5189598 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL14189092 | 0.68 | NOS3 (0.43) | MPO | |
| SCHEMBL14217532 | 0.67 | PKM (0.44) | MPOMAOAHTR2ADPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863959-B | P2X4 receptor antagonists | 日本化学药品株式会社 | 2021-11-30 | — | — | CN | disclosed |
| CN-111333588-A | P2X4 receptor antagonists | 日本化学药品株式会社 | 2020-06-26 | — | — | CN | disclosed |
| CN-110483423-A | P2X4 receptor antagonist | NIPPON CHEMIPHAR CO | 2019-11-22 | — | — | CN | disclosed |
| CN-108863959-A | P2X4 RECEPTOR ANTAGONIST | 日本化学药品株式会社 | 2018-11-23 | — | — | CN | disclosed |