Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259608 | 0.86 | AGTR1 (0.44) | HTR6AGTR1ADORA2AADORA1ALDH1A1 | |
| SCHEMBL28259247 | 0.85 | L3MBTL1 (0.47) | HTR6AGTR1ADORA2AADORA1KDM4E | |
| SCHEMBL28259260 | 0.84 | L3MBTL1 (0.46) | HTR6AGTR1ADORA2AADORA1KDM4E | |
| SCHEMBL28259245 | 0.83 | NOD2 (0.41) | HTR6AGTR1PIM1ALDH1A1TDP1 | |
| SCHEMBL28456977 | 0.83 | PCSK9 (0.42) | HTR6AGTR1ADORA2AADORA1KDM4E | |
| SCHEMBL28259259 | 0.83 | GBA1 (0.38) | PIK3CDPIK3CAPIK3CBPIK3CGGBA1 | |
| SCHEMBL28449123 | 0.82 | AGTR1 (0.41) | HTR6AGTR1ADORA2AADORA1KDM4E | |
| SCHEMBL28259257 | 0.82 | AGTR1 (0.41) | HTR6AGTR1ADORA2AADORA1KDM4E | |
| SCHEMBL28453278 | 0.81 | CXCL8 (0.40) | HTR6AGTR1ADORA2AADORA1PIM1 | |
| SCHEMBL28451888 | 0.81 | AGTR1 (0.40) | HTR6AGTR1ALDH1A1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947890-A | A method of preparing two substitution 4- aminocarbazole class compounds | 台州学院 | 2018-12-07 | — | — | CN | disclosed |