Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 6/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259245 | 0.89 | NOD2 (0.41) | PCSK9HTR6AGTR1GAACXCL8 | |
| SCHEMBL28259608 | 0.88 | AGTR1 (0.44) | PCSK9HTR6AGTR1GAACXCL8 | |
| SCHEMBL28449123 | 0.88 | AGTR1 (0.41) | PCSK9HTR6AGTR1GAACXCL8 | |
| SCHEMBL28259247 | 0.87 | L3MBTL1 (0.47) | PCSK9HTR6AGTR1GAACXCL8 | |
| SCHEMBL28451888 | 0.86 | AGTR1 (0.40) | PCSK9HTR6AGTR1GAACXCL8 | |
| SCHEMBL28259260 | 0.85 | L3MBTL1 (0.46) | PCSK9HTR6AGTR1GAACXCL8 | |
| SCHEMBL28259257 | 0.84 | AGTR1 (0.41) | PCSK9HTR6AGTR1GAACXCL8 | |
| SCHEMBL28453278 | 0.83 | CXCL8 (0.40) | PCSK9HTR6AGTR1GAACXCL8 | |
| SCHEMBL28260975 | 0.83 | PIK3CD (0.42) | PCSK9HTR6AGTR1GAACXCL8 | |
| SCHEMBL28260945 | 0.82 | HTR6 (0.49) | HTR6AGTR1GAACXCL8NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947890-B | Method for preparing disubstituted 4-aminocarbazole compound | 台州学院 | 2020-08-04 | — | — | CN | disclosed |